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KMID : 1084220160230040250
Journal of Rheumatic Diseases
2016 Volume.23 No. 4 p.250 ~ p.255
A Case of Infliximab-induced Multifocal Motor Neuropathy in a Patient with Rheumatoid Arthritis and Literature Review
Seo Bo-Mi

Jeong Yeong-Jin
Hong Seok-Chan
Kim Yong-Gil
Lee Chang-Keun
Yoo Bin
Abstract
Tumor necrosis factor (TNF) inhibitors are increasingly used in treatment of rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis, and inflammatory bowel diseases including Crohn¡¯s disease and ulcerative colitis. Rarely, anti-TNF therapy is associated with neurological complications, including both central and peripheral nervous system disorders. To the best of our knowledge, only one case of infliximab-associated multifocal motor neuropathy with conduction block in a patient with spondyloarthropathy has been reported to date in Korea. Here, we report on the case of a 58-year-old Korean woman affected by RA who developed multifocal motor neuropathy after infliximab treatment.
KEYWORD
Infliximab, Motor neuropathy, Rheumatoid arthritis
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